楊光教授
楊光，博士，生物與醫學工程學院教授。2009年于浙江大學獲得工學博士學位，美國加州大學洛杉磯分校生物工程系、美國北卡羅來納大學教堂山分校生物醫學工程系訪問學者。長期從事生物醫用材料、經皮藥物遞送方向的基礎和應用研究。主持國家自然科學基金面上項目、上海市自然科學基金等研究課題10余項；以通訊/第一作者在Advanced Materials、ACS Nano、Advanced Functional Materials等學術期刊發表論文40余篇；申請中國發明專利20余項及PCT國際專利1項。
研究方向：
1. 角蛋白基水凝膠及其在糖尿病創面修復中的應用
2. 經皮藥物遞送系統及其在皮膚相關疾病中的應用
榮譽及獲獎情況：
1. 2019年入選上海市浦江人才計劃
2. 2011年入選上海市晨光人才計劃
近年來承擔的主要項目情況：
1. 雙層水凝膠時序調控炎癥細胞行為促進糖尿病創面修復的作用與機制研究，國家自然科學基金面上項目
2. 可控透皮給藥治療類風濕關節炎及其減毒增效作用評價，上海市自然科學基金項目
3. 微針介導胺碘酮局部長效給藥治療心臟術后房顫，上海市科委浦江人才計劃項目
4. PLGA基儲庫微針用于心房局部長效給藥的研究，聚合物分子工程國家重點實驗室（復旦大學）開放研究課題基金
5. 角蛋白礦化制備高熒光納米金簇及汞離子檢測應用，中國博士后科學基金項目（一等）
6. 基于生物模板效應的BC/AgNPs功能復合材料的設計合成及性能研究，國家自然科學基金青年基金項目
7. 生物納米纖維基小徑血管的構建及其性能研究，上海市自然科學基金項目
8. 細菌纖維素基功能醫用納米材料的綠色合成及應用基礎研究，上海市教育委員會“晨光計劃”項目
9. 載銀納米纖維敷料的生物相容性研究，上海市教委“上海高校青年教師培養資助計劃”項目
近年來發表的代表性論著：
論文
2. Wang Wenshuo; Chen Yansong; Huang Liqi; Lu Ziyi; Muhammad Asad Ullah; Wei Lai; Yang Guang*, Reservoir Microneedle Patch Mitigates Postsurgical Atrial Fibrillation. Advanced Functional Materials, 2024, 231252.
3. Lu Ziyi; Du Shan; Li Jiaxun; Zhang Min; Nie Huali; Zhou Xiaojun; Li; Fulun; Wei Xinwei; Wang Jinqiang; Liu Fuyao; He Chuanglong*; Yang Guang*; Gu Zhen*, Langmuir–Blodgett-Mediated Formation of Antibacterial Microneedles for Long-Term Transdermal Drug Delivery. Advanced Materials, 2023, 2303388.
4. Shi Tongtong; Lu Hanzhi; Zhu Jianyong; Zhou Xiaojun; He Chuanglong*; Li Fulun*; Yang Guang*; Naturally derived dual dynamic crosslinked multifunctional hydrogel for diabetic wound healing, Composites Part B-Engineering, 2023, 257, 110687.
5. Chen Yansong; Li Ying; Yang Xuexia; Cao Zhangjun; Nie Huali; Bian Yonggang; Yang Guang*; Glucose-triggered in situ forming keratin hydrogel for the treatment of diabetic wounds, Acta Biomaterialia, 2021, 125: 208-218.
6. Du Shan; He Tiantian; Nie Huali*; Yang Guang*; High-performance wigs via the Langmuir–Blodgett deposition of keratin/graphene oxide nanocomposite, ACSApplied Materials & Interfaces, 2022, 14: 27233-27241.
7. Tang Ao; Li Ying; Yao Yiqian; Yang Xuexia; Cao Zhangjun; Yang Guang*；Injectable keratin hydrogels as hemostatic and wound dressing materials, Biomaterials Science, 2021,9:4169-4177.
8. Yang Guang; Chen Qian; Wen Di; Chen Zhaowei; Wang Jinqiang; Chen Guojun; Wang Zejun; Zhang Xudong; Zhang Yuqi; Hu Quanyin; Zhang Liang*; Gu Zhen*; A therapeutic microneedle patch made from hair-derived keratin for promoting hair regrowth, ACS Nano, 2019, 13: 4354-4360.
9. Li Ying; Cao Yu; Wei Lai; Wang Jinjie; Zhang Min; Yang Xuexia; Wang Wenshuo; Yang Guang*; The assembly of protein-templated gold nanoclusters for enhanced fluorescence emission and multifunctional applications, Acta Biomaterialia, 2020, 101: 436-443.
10. Cao Yu; Yao Yiqian; Li Ying; Yang Xuexia; Cao Zhangjun; Yang Guang*; Tunable keratin hydrogel based on disulfide shuffling strategy for drug delivery and tissue engineering,Journal of Colloid and Interface Science, 2019, 544: 121-129.
11. Li Yan; Song Kai; Cao Yu; Peng Chen*; Yang Guang*; Keratin-templated synthesis of metallic oxide nanoparticles as MRI contrast agents and drug carriers, ACS Applied Materials & Interfaces, 2018, 10: 26039-26045.
12. Chen Qian; Wang Chao; Zhang Xudong; Chen Guojun; Hu Quanyin; Li Hongjun; Wang Jinqiang; Wen Di; Zhang Yuqi; Lu Yifei; Yang Guang; Jiang Chen; Wang Jun; Dotti Gianpietro; Gu Zhen*; In situ sprayed bioresponsive immunotherapeutic gel for post-surgical cancer treatment, Nature Nanotechnology, 2019,14: 89-97.
13. Wang Jinjie; Ma Shuyi; Ren Jicun; Yang Jinxia; Qu Yi; Ding Derun; Zhang Min*; Yang Guang*; Fluorescence enhancement of cysteine-rich protein-templated gold nanoclusters using silver(I) ions and its sensing application for mercury(II), Sensors and Actuators B: Chemical, 2018,267: 342-350.
14. Yang Guang*; Wang Caixia; Hong Feng*; Yang Xuexia; Cao Zhangjun; Preparation and characterization of BC/PAM-AgNPs nanocomposites for antibacterial applications, Carbohydrate Polymers, 2015, 115: 636-642.
15. Yang Guang*; Xie Jianjian; Hong Feng; Cao Zhangjun; Yang Xuexia; Antimicrobial activity of silver nanoparticle impregnated bacterial cellulose membrane: Effect of fermentation carbon sources of bacterial cellulose, Carbohydrate Polymers, 2012, 87: 839-845.
16. Yang Guang*; Xie Jianjian; Deng Yunxia; Bian Yonggang; Hong Feng; Hydrothermal synthesis of bacterial cellulose/AgNPs composite: A “green” route for antibacterial application, Carbohydrate Polymers, 2012, 87: 2482-2487.
E-MAIL：gyang@dhu.edu.cn
